Biology 100 B 

syllabus 
lab schedule
assignments
links
 

Syllabus - Part 1 - Human genetics

part 2 - evolutionary medicine 
  part 3 - evolution of virulence part 4 - evolution of sex 

date topics  chapter
in
Genome
1/29

Introductions; definitions of "gene"

  
 1/30

The gene as the unit of heredity
Huntington's disease
Alkaptonuria
Mendelian inheritance
pedigree analysis (basic) (advanced)

 i - 4

 2/6
 Snow day

 2/8
 From genes to traits
Alkaptonuria and tyrosine metabolism
Why loss-of-function alleles are recessive
The 20 amino acids


5-9

 2/13
 From genes to traits, part 2
Huntington's disease
Why gain-of-function alleles are dominant
ABO blood groups, codominance		 .

 2/15
 From DNA to protein: transcription and translation
"Central Dogma"
DNA and molecular genetics
Structure of DNA		 .

 2/20
 Cholesterol, steroids, and the notion of a molecular switch
The endocrine system
Hormonal control of gene expression
The eukaryotic genome & regulation of gene expression

10-11

2/22
 QUIZ
What experimental embryology tells us about gene action during development

12
 2/27 Chromosomal genetics
Schematic representation of genes on a chromosome
Packing the DNA into chromosomes
The hereditary material is bound on Chromosomes
photomicrograph of human chromosomes & karyotype
schematic diagram of human chromosome and karyotype
What can our chromosomes tell us?
sex determination
tracing humans via the Y chromosome
The human Y chromosome
Tracing the history of Jews with the Y chromosome
Tracing Thomas Jefferson's descendants with the Y chromosome
Human and apes
Comparison of human and ape chromosomes
Which of our genes make us human?

 X&Y,
13, 15

3/1
 Population genetics

 18-22

3/6
 snow day

   to part 2 - evolutionary medicine

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