Presentation
Guidelines
Each pair of you will select one of the literature papers
below and present it to your classmates. The references for each paper
are provided here
so that your classmates will look at the paper ahead of time and come
to your
presentation
prepared with questions.
Prepare visual aids,
either a powerpoint presentation or transparencies, to assist you in
illustrating your points. Make sure that your computer or presentation
is properly set up and ready to go BEFORE class begins.
Presentations
will be 20 minutes, plus 5 minutes for questions. You will want
to spend a couple of minutes discussing the
background and clearly stating the question or hypothesis, then explain
the methods used, and finally show the results from the paper and discuss
them. Are the data good? Are the conclusions valid? Might the authors
have left out an important control or over-interpreted the results?
Conversely, if you think it is a good paper, explain what about it is
unique,
inventive, or thorough. What is the "big picture"?
Sept 21st |
Pauling et al.(1951) The structure of proteins: two
hydrogen-bonded helical conformations of the polypeptide chain. PNAS 37,
205-211.
presented by Damarys and Louise
|
Sept 28th |
Nguyen et al. (1995) Prion proteins induce alpha-helix
to beta-sheet conformational transitions. Biochemistry 34,
4186-4192.
presented by Naa and Blanca
|
Oct 5th |
Montelione et al. (1992) Solution structure of murine epidermal growth factor determined by NMR spectroscopy and refined by energy minimization with restraints. Biochemistry 31, 236-249.
presented by Kat and Kiri-Lin |
Oct 12th |
Schlichting et al.(2000) The catalytic pathway of cytochrome
P450cam at atomic resolution. Science 287,
1615-1622.
presented by Megan and Natalie
|
Oct 19th |
Heim et al. (1994) Wavelength mutations and posttranslational
autoxidation of green fluorescent protein. PNAS 91,
12501-12504.
presented by Kelley and Christina
|
Oct 26th |
Watson and Crick (1953) Molecular structure of nucleic acids.
Nature 171, 737-738.
presented by Frances and Yu
|
Nov 2nd |
Beal and Dervan (1991) Second structural motif for recognition
of DNA by oligonucleotide-directed triple-helix formation. Science 251, 1360-1363.
presented by Lindiwe and Otema
|
Nov 9th |
Cech (2000)The ribosome is a ribozyme. Science 289,
5481.
presented by Taylor and Cathy and Priscilla
|
Nov 16th |
Poklar et al. (1996) Influence of cisplatin intrastrand crosslinking
on the conformation, thermal stability, and energetics of a 20-mer
duplex. PNAS 93, 7606-7611.
presented by Zainab and Lindsay
|
Nov 30th |
Greisman and Pabo (1997) A general strategy for selecting high-affinity zinc finger proteins for diverse DNA target sites. Science 275,
657-661.
presented by Eva and Chrissy
|
|