Research Overview
In my research, I use a variety of chemical, physical, and biochemical tools to answer relevant biological questions. At this intersection between different fields, I hope to bring a different perspective and experience to bear on interesting scientific puzzles.
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In my graduate work, I examined long-range charge transfer as a mechanism for oxidative base damage in DNA with Jackie Barton at Caltech. We found that damage could be spread out around the genome, even to remote sites in nucleosomes and packaged DNA. These discoveries led me to begin thinking about the mechanisms of DNA damage and repair in eukaryotic systems. As an Irvine Postdoctoral Fellow at Occidental College, I used Atomic Force Microscopy to examine bacterial predation with two wonderful collaborators and several talented undergraduate research students. I have continued this work in the Chemistry Department at Mount Holyoke college with help from more wonderful undergraduate research students. |
Please click on any of the tabs above to learn more about my research interests and coworkers.