Mount Holyoke College

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On the bottom of each movie will be a control bar. The movie will play automatically after loading. If it looks a little "jerky", you may have better results by clicking and holding your cursor on the "play" arrow, and sliding along the bottom, controlling the speed of the movie with your mouse.

Class Videos

Sea urchin embryos:skeletons and polarized light. When viewed under polarized light, the internal calcium carbonate skeleton of larval sea urchins glows, because the mineral is birefringent. (2 videos on this page)

Sea urchin embryos: a vegetal view of the developing gut. This movie gives an interesting perspective on how a sea urchin embryos makes the long gut tube.

Flatworm Regeneration. Planarian flatworms have remarkable regenerative abilities, and these videos show a two-headed animal.(2 videos on this page)

Keratocyte Locomotion. Cells isolated from a killifish scale migrate in culture. The movies were made in the Bio 305 lab (9/22,23/99), and both a low-power and high-power view of lamellipodial locomotion are shown. (2 videos on this page)

Other Videos

Killifish Deep Cell Migration. The embryos of the killifish Fundulus heteroclitus are large and transparent, making them ideal for filming. These three sequences show individual deep cells migrating in the yolk sac of an embryo. (3 videos on this page)

Deep Cells Migrating to the Site of a Wound. A low-power view of many killifish deep cells migrating directionally in response to a small wound made in the overlying epithelium.

Animal Mitosis. One of the most beautiful "dances" in the biological world, the division of replicated chromosomes was filmed in newt lung epithelial cells by Conly Rieder and his lab.

Abnormal Animal Mitosis. What happens when mitosis goes awry? This video, also filmed by the Rieder lab, shows a mitosis where one chromosome becomes lost, and does not align properly on the spindle.

Syncytial Cleavage. In developing fruit fly embryos, hundreds of nuclei divide synchronously, in common cytoplasm. Bill Therkauf injected a fluorescent marker for DNA, labeling all of the chromosomes. In this amazing sequence, you can watch a population of nuclei go through mitosis in concert.

Sea Urchin Cleavage. This video, filmed in Rachel Fink's lab at Mount Holyoke, shows a single fertilized sea urchin egg undergoing the early divisions to create a multicellular blastula.